Epilepsy is an umbrella term encompassing a huge number of seizure disorders.
Whether they are intense physical seizures or hard-to-perceive absence seizures, all seizures can be dangerous. Around 15 million people, thirty percent of people diagnosed with epilepsy, have seizures that are uncontrolled by currently available medications.
Professor Cameron Metcalf is Associate Director of the Anticonvulsant Drug Development (ADD) Program based at the University of Utah. His team use preclinical seizure models of epilepsy to test over 800 novel anticonvulsant compounds per year. In this excerpt from the webinar Evaluation of Novel Therapies Using Spontaneous Seizure Models, Cameron discusses the use of telemetry in improving the process of testing potential anticonvulsants.
In this excerpt, Cameron discusses:
- The importance of having a skilled surgeon
- Using video-EEG to track seizure activity
- Seizure review and automation
- Reusing telemeters
- Setting up crossover study design for mini-clinical trials
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